2014
Tendon-to-Bone Healing in Rotator Cuff Repair
Chang et al. · J Orthop Res
Accelerated structural restoration in rat rotator-cuff model.
Most Researched
Lot CB26-04-001MFG 04/2026
About BPC-157
Synthetic 15-amino-acid peptide derived from a fragment of human gastric protein. Supplied as a 10 mg lyophilized powder for in-vitro research.
The compound has been the subject of more than two hundred peer-reviewed reports examining its action across models of tissue injury, gastrointestinal cytoprotection, and tendon-to-bone healing. Reports converge on involvement of nitric oxide signaling and modulation of growth-factor expression.
Each lot is independently tested for both purity (HPLC + ESI-MS) and endotoxin (LAL kinetic chromogenic) before listing.
Identity & Specifications
Sequence
GEPPPGKPADDAGLV
Length
15 residues
Formula
C₆₂H₉₈N₁₆O₂₂
Mol. weight
1419.55 g/mol
CAS
137525-51-0
PubChem
108101
Purity (HPLC)
≥ 99.1%
Endotoxin (LAL)
0.18 EU/mg
Reconstitution
Bacteriostatic water
Storage
−20°C, sealed
Certificate of Analysis · Lot CB26-04-001
| Parameter | Method | Spec | Result |
|---|---|---|---|
| Identity | ESI-MS | Conforms | Pass |
| Purity | HPLC-UV 220 nm | ≥ 98.0% | 99.1% |
| Endotoxin | LAL kinetic | < 0.5 EU/mg | 0.18 EU/mg |
| Bioburden | Microbial count | < 100 CFU/g | < 10 CFU/g |
| Water content | Karl Fischer | ≤ 6.0% | 3.91% |
| Appearance | Visual | White lyophilized cake | Conforms |
Selected References
- Sikiric P, et al. A new gastric juice peptide, BPC. J Physiol Paris, 1993.
- Chang CH, et al. The promotion of tendon-to-bone healing of BPC-157. J Orthop Res, 2014.
- Krivic A, et al. Achilles detachment and stable gastric pentadecapeptide BPC-157. J Orthop Res, 2006.
- Pevec D, et al. BPC-157 attenuates muscle crush. Bosn J Basic Med Sci, 2010.
- Brcic L, et al. BPC-157 effects on gastric ulcer healing. J Physiol Pharmacol, 2009.
Recent Research Highlights
2010
Skeletal Muscle Crush Injury
Pevec et al. · Bosn J Basic Med Sci
Attenuated histological damage and faster recovery of contractile function.
2009
Gastric Ulcer Healing
Brcic et al. · J Physiol Pharmacol
Modulatory effects on epithelial migration and capillary density.
1993
Original BPC Characterization
Sikiric et al. · J Physiol Paris
Established the peptide's stability profile and proteolytic resistance.
⊕
3rd Party Tested
Independent lab
≥98%
HPLC Purity
+ ESI-MS
LAL
Endotoxin
LAL kinetic
§
Lot-traceable
In COA library
§ Research-Use Compliance
This compound is supplied by Crescent Bioresearch LLC for laboratory research and pre-clinical use only. It is not a drug, dietary supplement, food, or cosmetic, and has not been approved by the U.S. Food and Drug Administration for human or veterinary administration, diagnosis, treatment, or prevention of any condition.
The pharmacological, toxicological, and stability properties of this compound have not been fully studied. It must therefore be handled only by personnel trained in laboratory safety practices.
The purchaser bears sole responsibility for ensuring that all handling, storage, and intended use comply with applicable local, state, and federal regulations. Full terms are set out in the RUO Disclaimer and Terms of Service.
