KLOW is a single 80 mg lyophilized vial containing four compounds: GHK-Cu, BPC-157, TB-500 and KPV. GHK-Cu is the predominant component; exact proportions for the vial you receive are printed on that lot's certificate of analysis.

Each component is assayed by HPLC-UV at 220 nm for purity under USP , identity is confirmed by FTIR under USP , and bacterial endotoxin is measured by gel-clot LAL under USP . Testing is performed by an accredited third-party laboratory, not in house.

Why are these four compounds combined?

Each has been studied in a different part of the matrix-remodelling and inflammatory-signalling literature — copper transport and matrix remodelling, angiogenic and gastrointestinal models, actin sequestration, and melanocortin-pathway inflammatory signalling. Combining them into one vial is a formulation convenience for researchers designing multi-component protocols; it is not evidence of a combined effect.

Is KLOW for human use?

No. KLOW is supplied for research use only and is not for human or veterinary use.

Sequence	MRWQEMGYIFYPRKLR
Length	16 residues
Formula	C₁₀₁H₁₅₂N₂₈O₂₂S₂
Mol. weight	2174.59 g/mol
CAS	1627580-64-6
PubChem	146675088

Cellular

MOTS-c

MOTS-c is a 16-amino-acid peptide encoded within the mitochondrial 12S rRNA, identified in 2015 as one of the first known mitochondrial-derived peptides (MDPs). It is implicated as a regulator of metabolic homeostasis and mitochondrial-to-nuclear retrograde signaling.

Molecular structure

Sequence MRWQEMGYIFYPRKLR

What it has been studied for

Research interest centers on AMPK-pathway signaling, insulin-sensitivity studies, and mitochondrial-encoded signaling biology. The peptide is among the most-studied mitochondrial-derived peptides in metabolic research.

References

Citations for this compound are being verified against the primary sources before they are listed. Nothing appears here until it has been checked.

Back to MOTS-c

For Research Use Only. Not for human or veterinary use.