KLOW is a single 80 mg lyophilized vial containing four compounds: GHK-Cu, BPC-157, TB-500 and KPV. GHK-Cu is the predominant component; exact proportions for the vial you receive are printed on that lot's certificate of analysis.

Each component is assayed by HPLC-UV at 220 nm for purity under USP , identity is confirmed by FTIR under USP , and bacterial endotoxin is measured by gel-clot LAL under USP . Testing is performed by an accredited third-party laboratory, not in house.

Why are these four compounds combined?

Each has been studied in a different part of the matrix-remodelling and inflammatory-signalling literature — copper transport and matrix remodelling, angiogenic and gastrointestinal models, actin sequestration, and melanocortin-pathway inflammatory signalling. Combining them into one vial is a formulation convenience for researchers designing multi-component protocols; it is not evidence of a combined effect.

Is KLOW for human use?

No. KLOW is supplied for research use only and is not for human or veterinary use.

Sequence	AEDG
Length	4 residues
Formula	C₁₄H₂₂N₄O₉
Mol. weight	390.35 g/mol
CAS	307297-39-8
PubChem	219042

Immunological

Epithalon 50 mg

Epithalon is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) developed at the St. Petersburg Institute of Bioregulation and Gerontology. This 50 mg presentation is supplied for extended research protocols requiring a larger quantity.

Molecular structure

Sequence AEDG

What it has been studied for

Identical chemistry and quality to the 10 mg presentation; supplied in a single lyophilized vial. Research interest centers on telomere biology, pineal-gland physiology, and pre-clinical longevity models.

References

Khavinson VK, Bondarev IE, Butyugov AA. Epithalon peptide induces telomerase activity and telomere elongation in human somatic cells. Bulletin of Experimental Biology and Medicine 2003;135:590–592. link.springer.com
Anisimov VN, Khavinson VKh, et al. Effect of Epitalon on biomarkers of aging, life span and spontaneous tumor incidence in female Swiss-derived SHR mice. Biogerontology. link.springer.com
Anisimov VN, et al. Pineal peptide preparation epithalamin increases the lifespan of fruit flies, mice and rats. Mechanisms of Ageing and Development 1998. sciencedirect.com

Back to Epithalon 50 mg

For Research Use Only. Not for human or veterinary use.