SequenceAEDG
Length4 residues
FormulaC₁₄H₂₂N₄O₉
Mol. weight390.35 g/mol
CAS307297-39-8
PubChem219042

Immunological

Epithalon 10 mg

Epithalon is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) developed at the St. Petersburg Institute of Bioregulation and Gerontology as a synthetic analog of the pineal-gland peptide complex Epithalamin.

Molecular structure

Sequence AEDG

What it has been studied for

Research interest centers on telomere biology, pineal-gland physiology, and pre-clinical longevity models. The peptide has been the subject of decades of Russian-language gerontology research with translated reviews available.

References

  1. Khavinson VK, Bondarev IE, Butyugov AA. Epithalon peptide induces telomerase activity and telomere elongation in human somatic cells. Bulletin of Experimental Biology and Medicine 2003;135:590–592. link.springer.com
  2. Anisimov VN, Khavinson VKh, et al. Effect of Epitalon on biomarkers of aging, life span and spontaneous tumor incidence in female Swiss-derived SHR mice. Biogerontology. link.springer.com
  3. Anisimov VN, et al. Pineal peptide preparation epithalamin increases the lifespan of fruit flies, mice and rats. Mechanisms of Ageing and Development 1998. sciencedirect.com
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